Mirvaso (brimonidine) topical gel, 0.33%

Brimonidine acts very quickly when you apply to the skin within about 30 minutes.8:20–8:25

One thing that happens to some people: they get kind of like an intense rebound worsening of the redness.8:25–8:31

One of the biggest complaints I hear from people who use Brimonidine for their redness is that it's a little bit too unnatural looking and that it clamps down more I guess intensely and they get kind of a whitening effect where their skin looks pale, blanched.8:35–8:39