Product profile

Neutrogena

Rapid Wrinkle Repair Regenerating Anti-Wrinkle Retinol Cream + Hyaluronic Acid

2Mentions
1Creators
$27.99Price
Typefacial moisturizer
Finish
RetailersNeutrogena.com, Walmart
Key ingredientsRetinol, Hyaluronic Acid, Glycerin, Dimethicone, Sodium Hyaluronate, Ascorbic Acid, BHT, Phenoxyethanol, Caprylyl Glycol, Fragrance

Creator evidence

Doctorly

board-certified dermatologist · skincare focus · 5yr on YouTube

tried and true · drugstore · everyday, drugstore, luxury · aging, dry, normal, oily, sensitive
This one is a fond one for me. It's the first retinol product I ever used.▶ 12:06–12:11
It is effective. They have a lot of studies backing it up.▶ 12:16–12:18
This retinol is paired with a lot of hydrating ingredients. So it offsets irritation especially for someone who's just starting a retinol. I think this is a perfect pick.▶ 12:18–12:22
They have some really fascinating internal studies that show its retinol activity on the skin and actually having increased retinol activity actually acting in your skin compared to other moisturizers that have retinol in it.▶ 12:25–12:30
Source: Best moisturizers of the year: doctorly favorites of 2025 · Jan 2026
tried and true · drugstore · night, anti-aging, drugstore · dry
Both of these formulas are they have encapsulated retinol at concentrations of unknown.▶ 4:30–4:38
The rapid wrinkle repair does have a sugar complex that helps to accelerate or increase the penetration of the retinol into the skin.
The Neutrogena one is the thickest of the three.
If you're someone who has dry skin and you always appreciate a little bit of an extra hug, Neutrogena is probably going to be the one that sits best with you.▶ 10:01–10:04
Just me being drier skin, I prefer the Neutrogena one.▶ 10:46–10:51
They have some internal data showing increased expression of CRABP2, which is a molecule that transfers retinol or retinoic acid into the nucleus so that it can act on the retinoic acid receptors.▶ 12:54–13:01
They also have like 20 patents on the retinol itself and they also have like a hundred studies on the retinol as well.▶ 13:23–13:30
They show that it slowly releases throughout the day onto the skin.▶ 13:30–13:35
Source: Derm compares Olay, Neutrogena, and RoC retinol products · Dec 2025