Product profile

skinbetter science

AlphaRet Overnight Cream

2Mentions
1Creators
$170Price
Typeface cream
Finish
Retailersskinbetter.com, store.skinbetter.com
Key ingredientsretinoid, lactic acid, glycolic acid, vitamin C, vitamin E, coenzyme Q10, ceramides, squalane, niacinamide, hyaluronic acid

Creator evidence

Dr. Sarah Sheu

board-certified dermatologist · based in Seattle · 1yr on YouTube

holy grail · luxury · antiaging, acne, budget, luxury, drugstore · sensitive, normal, oily, combination, dry
I like that there's a published study that was done on this exact product comparing it to the gold standard retinoid for anti-aging, which is prescription tretinoin.▶ 5:08–5:15
At 4, 8, and 12 weeks, the AlphaRet side was non-inferior to tretinoin at improving fine lines, facial redness, facial discoloration, and skin tone.
It was also less irritating than both retinol and tretinoin.
Unlike tretinoin which reduced skin hydration, AlphaRet increased skin hydration.
I really like this product because I have sensitive skin even though I hate how expensive it is.
If I completely ignore prices and I live in La La Land, it is my favorite over-the-counter retinoid.
My sensitive skin tolerates it well.
I like how the color isn't as scary as the stronger retinal's too.
Source: Dermatologist: Best Retinoids at Every Price · Mar 2026
mentions · luxury · summer
The Skin Better Alpharet overnight cream is $145 for 30 mls.▶ 10:06–10:12
Source: Dermatologist's summer skincare hits and flops · Aug 2025