AlphaRet Overnight Cream
SUMMARY OF REVIEWS
Skinbetter Science's AlphaRet Overnight Cream, at $145 for 30 ml, is a retinoid alternative backed by a published study showing it's non-inferior to prescription tretinoin for fine lines, redness, and discoloration at 4, 8, and 12 weeks. Board-certified dermatologist Dr. Sarah Sheu notes it's less irritating than retinol or tretinoin and actually increases skin hydration, unlike tretinoin. She calls it her favorite over-the-counter retinoid for sensitive skin, despite the high price and a slight odd smell that fades.
FULL REVIEWS
POSITIVE
- “I like that there's a published study that was done on this exact product comparing it to the gold standard retinoid for anti-aging, which is prescription tretinoin”5:08–5:15
- “At 4, 8, and 12 weeks, the AlphaRet side was non-inferior to tretinoin at improving fine lines, facial redness, facial discoloration, and skin tone”
- “It was also less irritating than both retinol and tretinoin”
- “Unlike tretinoin which reduced skin hydration, AlphaRet increased skin hydration”
- “I really like this product because I have sensitive skin even though I hate how expensive it is”
- “If I completely ignore prices and I live in La La Land, it is my favorite over-the-counter retinoid”
- “My sensitive skin tolerates it well”
- “I like how the color isn't as scary as the stronger retinal's too”
- Source: Dermatologist: Best Retinoids at Every Price - Mar 14, 2026
- “The Skin Better Alpharet overnight cream is $145 for 30 mls”10:06–10:12
- Source: Dermatologist's summer skincare hits and flops - Aug 9, 2025
MIXED / NEGATIVE
No negative reviews yet — creators have only had good things to say.
WHAT CREATORS SAY
- Consensus
- 4.5 / 5 from 2 creator reviewsGrailPeople ratings based on creator reviews.
Product details
Details
- Type
- face cream
- Finish
- —
- Shade
- —
- Key ingredients
- retinoid, lactic acid, glycolic acid, vitamin C, vitamin E, coenzyme Q10, ceramides, squalane, niacinamide, hyaluronic acid
Links