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4.2Superoxide Dismutase 3 Enzyme Mist (SDEM3)
  • “This did not disappoint. Well, at least formula-wise, it did not disappoint”4:57–5:00
  • “I do actually prefer this to the SDSM, which is a lot for me to say, because I can't overstate how much I love this previously”5:13–5:20
  • “There's definitely upgrade in the formula”
  • “This has a real fast impact, I find, on redness, especially the winter cold redness. It's just is so calming”6:12–6:18
  • “My one complaint, which I feel is a significant oversight, is the misting function of this is abysmal”5:42–5:51
  • “It's like I can't use it by misting it on my face, because it comes out in one incredibly strong and focused stream”5:54–5:58
  • “The way I apply this, and this is the best way to do it, I apply on my hands first and just use it like I would a regular hydrating toner or essence”6:02–6:06
  • Source: My 2025 skincare favorites - Jan 11, 2026
Brand note

NIOD is a science-heavy skincare brand that focuses on targeted, high-concentration formulas rather than all-in-one products. Its Fractionated Eye Contour Concentrate stands out as a long-term investment for depuffing, smoothing fine lines, and hydrating, with a lightweight texture that rewards consistency. The brand suits anyone willing to commit to a multi-step routine and pay for advanced ingredients; the trade-off is that results are gradual and products require patience.

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